正常和冲击伤大鼠气道及肺的扫描电镜观察

在4m长模拟激波管内电雷管引爆50gTNT炸药产生冲击波,致伤管口外40cm处大鼠,伤后立即做血气检查,肺组织及气道取材作光镜及扫描电镜观察。结果表明:冲击伤后大鼠血气变化明显;可见程度不一的肺出血、水肿、肺泡隔撕裂。扫描电镜下可见肺泡隔上毛细血管破裂,红细胞逸出;肺泡隔破坏残留“索条”状结构;气管、支气管粘膜上皮层有剥脱及裂隙形成。对其发生机理进行了分析。

A Scanning Electron Microscopic Study of the Air-way and Lungs of Normal and Blast Injured Rats

10 adult female rats were used to study blast injuries of the air-way and lung. The conclusions are as follows. 1. There was significant difference in arterial blood gas analysis between the normal control and injury group. 2. The une-venness in the lung damage, bleeding, tear of the alveolar septa induced by the air shock wave was predominant, by scanning electron microscopy (SEM) as well as by the light microscopy (LM) . The bleeding may be due to the capillary rupture of alveolar septa. The' rope-like' structures seen might represent the fibre component in the septa which had more resistance to the local force and remained after the other components were wiped away by explosion. 3. Striping and fissure of the epithelium of trachea and bronchi of the injured group were detected. 4. The pathological changes observed with SEM were compared to those with LM.