Exercise training increases respiratory muscle strength and exercise capacity in patients with chronic obstructive pulmonary disease and respiratory muscle weakness |
| |
| Institution: | 1. Division of Respiratory Therapy, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan;2. Department of Chinese Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan;3. School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan;4. Division of Pulmonary Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan;5. School of Medicine, Tzu-Chi University, Hualien, Taiwan;6. Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan;1. Gachon University, College of Nursing, Incheon, South Korea;2. Office of Hospital Information, Seoul National University Hospital, Seoul, South Korea;3. Division of Cardiology, Department of Internal Medicine, Gil Medical Center, Gachon University, College of Medicine, Incheon, South Korea;4. Division of Cardiology, Department of Internal Medicine, College of Medicine, Hanyang University Medical Center, Seoul, South Korea;5. Chonnam National University, College of Nursing, Gwangju, South Korea;6. Department of Nursing, Hanyang University Medical Center, Seoul, South Korea;7. Biostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, Korea;8. Gachon University Gil Medical Center, Incheon, South Korea;9. Mercer University, Georgia Baptist College of Nursing, Atlanta, USA;1. Department of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, United States;2. Department of Medicine, Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States;3. Centers for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, United States;4. Schools of Medicine and Public Health, Brown University, Providence, RI, United States;1. Department of Respiratory Therapy, Georgia State University, 140 Decatur Street P.O. Box 4019, Atlanta, GA 30302-4019, USA;2. Department of Physical Therapy, Georgia State University, Atlanta, GA, USA;1. Department of Internal Medicine, Saint Vincent Hospital, Worcester, Massachusetts United States, 01608;2. Division of Pulmonary and Critical care, Mayo Clinic, Rochester, Minnesota, Massachusetts United States, 55902;3. Department of Burns and Plastic Surgery, All India Institute of Medical Sciences, Raipur, Chhattisgarh, 492099, India;1. Department of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States;2. Department of Cardiovascular Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States;3. University College Cork School of Medicine, College Road, Cork T12 K8AF, Ireland |
| |
| Abstract: | BackgroundHow respiratory muscle strength influences the effectiveness of pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD) is unclear.ObjectiveTo investigate the benefits of PR in subjects with COPD according to respiratory muscle strength.MethodsNinety-seven subjects with COPD were evaluated using maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), pulmonary function tests, the cardiopulmonary exercise test (CPET), and the St. George's Respiratory Questionnaire (SGRQ). Subjects were divided into four groups: 1 (normal MIP and MEP); 2 (low MIP); 3 (low MEP); and 4 (low MIP and MEP). Subjects underwent PR for 3 months; MIP, MEP, SGRQ, and CPET were evaluated post-PR.ResultsSubjects with both poor MIP and MEP had the highest dyspnea score, lowest exercise capacity, and poorest health-related quality of life (HRQoL). PR improved exercise capacity and HRQoL in all groups, with more improvement in MIP, MEP, tidal volume (on exercise), and dyspnea (at rest) in subjects with both low MIP and MEP.ConclusionsPatients with respiratory muscle weakness had worse dyspnea, lower exercise capacity, and poorer HRQoL at baseline. Exercise training improved respiratory muscle strength with concurrent improvement of exercise capacity, HRQoL, and dyspnea score. Subjects with both poor baseline MIP and MEP showed greater benefits of PR. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
