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MOLECULAR IDENTIFICATION OF Bartonella henselae IN A SERONEGATIVE CAT SCRATCH DISEASE PATIENT WITH AIDS IN RIO DE JANEIRO, BRAZIL
Authors:Alexsandra R.m. Favacho  Isabelle Roger  Amanda K. Akemi  Adonai A. Pessoa  JR.   Andrea G. Varon  Raphael Gomes  Daniela T. Godoy  Sandro Pereira  Elba R.s. Lemos
Affiliation:(1) Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz (IOC)/FIOCRUZ;(2) Instituto de Pesquisa Clínica Evandro Chagas (IPEC);(3) Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos (LAPCLIN-DERMZOO), Instituto de Pesquisa Evandro Chagas (IPEC); FIOCRUZ, Rio de Janeiro, RJ, Brasil
Abstract:Bartonella henselae is associated with a wide spectrum of clinicalmanifestations, including cat scratch disease, endocarditis and meningoencephalitis,in immunocompetent and immunocompromised patients. We report the first molecularlyconfirmed case of B. henselae infection in an AIDS patient in stateof Rio de Janeiro, Brazil. Although DNA sequence of B. henselae hasbeen detected by polymerase chain reaction in a lymph node biopsy, acute andconvalescent sera were nonreactive.
Keywords:Bartonella henselae   Cat scratch disease   Human immunodeficiency virus   Molecular diagnosis   Rio de Janeiro   Brazil
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