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MOLECULAR IDENTIFICATION OF Bartonella henselae IN A SERONEGATIVE CAT SCRATCH DISEASE PATIENT WITH AIDS IN RIO DE JANEIRO, BRAZIL
Authors:Alexsandra Rm Favacho  Isabelle Roger  Amanda K Akemi  Adonai A Pessoa  JR  Andrea G Varon  Raphael Gomes  Daniela T Godoy  Sandro Pereira  Elba Rs Lemos
Institution:(1) Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz (IOC)/FIOCRUZ;(2) Instituto de Pesquisa Clínica Evandro Chagas (IPEC);(3) Laboratório de Pesquisa Clínica em Dermatozoonoses em Animais Domésticos (LAPCLIN-DERMZOO), Instituto de Pesquisa Evandro Chagas (IPEC); FIOCRUZ, Rio de Janeiro, RJ, Brasil
Abstract:Bartonella henselae is associated with a wide spectrum of clinical manifestations, including cat scratch disease, endocarditis and meningoencephalitis, in immunocompetent and immunocompromised patients. We report the first molecularly confirmed case of B. henselae infection in an AIDS patient in state of Rio de Janeiro, Brazil. Although DNA sequence of B. henselae has been detected by polymerase chain reaction in a lymph node biopsy, acute and convalescent sera were nonreactive.
Keywords:Bartonella henselae  Cat scratch disease  Human immunodeficiency virus  Molecular diagnosis  Rio de Janeiro  Brazil
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