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Regenerative Endodontics: A Potential Solution for External Root Resorption (Case Series)
Affiliation:1. Department of Endodontics, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel;2. Smile Medical Services Ltd, Ashdod, Israel;3. Department of Orthodontics, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel;4. Ruth and Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel;5. Department of Endodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel;1. Department of Oral Health Sciences, Endodontology, Katholieke Universiteit Leuven, Leuven, Belgium;4. Department of Oral Health Sciences, Orthodontics, Katholieke Universiteit Leuven, Leuven, Belgium;6. Department of Translational Cell and Tissue Research, Katholieke Universiteit Leuven, Leuven, Belgium;2. Biomaterials, BIOMAT, Leuven, Belgium;3. Laboratory of Morphology, Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium;1. Department of Endodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio;2. Department of Endodontics, College of Dentistry, Qassim University, Qassim, Saudi Arabia;1. Advanced Specialty Education Programs in Endodontics, School of Dentistry, Loma Linda University, Loma Linda, California;2. Department of Endodontics, UCLA School of Dentistry, Los Angeles, California;3. Department of Advanced Oral Sciences and Therapeutics, Division of Endodontics, School of Dentistry, University of Maryland, Baltimore, Baltimore, Maryland;4. Advanced Specialty Education Programs in Oral and Maxillofacial Surgery, School of Dentistry, Loma Linda University, Loma Linda, California;1. Department of Cariology, Restorative Sciences, and Endodontics, University of Michigan School of Dentistry, Ann Arbor, Michigan;2. Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil;3. Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil;4. Department of Dental Materials and Prosthodontics, Araraquara School of Dentistry, São Paulo State University, Araraquara, São Paulo, Brazil;1. Department of Endodontics and Oral Biology, Stony Brook University School of Dental Medicine, Stony Brook, New York;2. Private Practice, Stony Brook, New York;3. Department of Advanced Oral Sciences and Therapeutics, School of Dentistry, University of Maryland, Baltimore, Maryland;4. Private Practice, Centreville, Virginia
Abstract:IntroductionRegenerative endodontic procedures (REPs) are aimed to treat apical periodontitis and promote root maturation of immature necrotic teeth. However, REPs are not intended to be a primary indication for treating or arresting external root resorption (ERR). The purpose of this study was to describe REP treatment in the cessation of ERR.MethodsFour cases (5 teeth) of posttraumatic immature teeth diagnosed with necrotic pulp and apical periodontitis or chronic apical abscess were treated with REPs using plasma-rich fibrin as a scaffold. All the teeth showed ERR and have been followed up to 3 years.ResultsThis case series shows how REPs arrested ERR. In 3 of the cases, replacement resorption was arrested, thus avoiding complications of ankylosis and the need for decoronation.ConclusionsIn addition to the known advantages of REPs, we show that REPs are a promising treatment modality for arresting ERR, warranting further clinical trials.
Keywords:Ankylosis  dental trauma  external inflammatory root resorption  platelet-rich fibrin  replacement resorption  regenerative endodontic procedure
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