Prevalence of Apical Periodontitis and Conventional Nonsurgical Root Canal Treatment in General Adult Population: An Updated Systematic Review and Meta-analysis of Cross-sectional Studies Published between 2012 and 2020 |
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| Institution: | 1. University of Belgrade, School of Dental Medicine, Department of Pathophysiology, Belgrade, Serbia;2. University of Belgrade, School of Dental Medicine, Department of Biology and Human Genetics, Belgrade, Serbia;3. University of Belgrade, School of Dental Medicine, Central Library, Belgrade, Serbia;4. University of Belgrade, School of Dental Medicine, Laboratory for Basic Research, Belgrade, Serbia;6. University of Belgrade, School of Dental Medicine, Department for Medical Statistics and Informatics, Belgrade, Serbia;5. University of Belgrade, School of Dental Medicine, Department of Restorative Odontology and Endodontics, Belgrade, Serbia;1. Department of Periodontics, University of Washington, Seattle, Washington;2. Private Practice, Indianapolis, Indiana;3. Department of Endodontics, University of Texas Health San Antonio, San Antonio, Texas;4. Department of Periodontics, University of Texas Health San Antonio, San Antonio, Texas;1. Department of Conservative Dentistry and Endodontics, Thai Moogambigai Dental College and Hospital, Dr. MGR Educational and Research Institute, Chennai, India;2. Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada;3. Department of Dentistry, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada;1. Department of Endodontics, Faculty of Odontology, Malmö University, Malmö, Sweden;2. Department of Statistics, Lund University School of Economics and Management, Lund University, Lund, Sweden;3. Department of Endodontology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;1. Unidade de Investigação em Ciências Orais e Biomédicas, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal;2. Centro de Estudo de Medicina Dentária Baseada na Evidência, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal;3. Instituto de Implantologia, Lisbon, Portugal;4. Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada;6. LIBPhys-FCT UID/FIS/04559/2013, Lisbon, Portugal;5. Department of Endodontics, School of Dentistry, Grande Rio University, Rio de Janeiro, Brazil;7. Department of Oral Health, Brazilian Military Police, Minas Gerais, Brazil;1. Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Faculdade de Medicina Dentária, Universidade de Lisboa, Portugal;2. Centro de Estudo de Medicina Dentária Baseada na Evidência, Faculdade de Medicina Dentária, Universidade de Lisboa, Portugal;3. Instituto de Implantologia, Lisboa, Portugal;4. LIBPhys-FCT UID/FIS/04559/2013, Lisboa, Portugal;5. Department of Endodontics, School of Dentistry, Grande Rio University, Rio de Janeiro, Brazil;6. Department of Endodontics, Rio de Janeiro State University, Rio de Janeiro, Brazil;7. Faculdade de Medicina Dentária, Universidade de Lisboa, Portugal;8. Dental Specialty Center, Brazilian Military Police, Minas Gerais, Brazil;1. Department of Pathophysiology, School of Dental Medicine, University of Belgrade, Belgrade, Serbia;2. Department of Biology and Human Genetics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia;3. Central Library, School of Dental Medicine, University of Belgrade, Belgrade, Serbia;4. Department of Oral Surgery, School of Dental Medicine, University of Belgrade, Belgrade, Serbia;5. Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada |
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| Abstract: | IntroductionThis study aimed to summarize data on apical periodontitis (AP) and nonsurgical root canal treatment (NSRCT) prevalence and risk factors related to age, gender, and quality of restorative and endodontic treatment in the general population from cross-sectional studies published between 2012 and 2020.MethodsAn electronic search was performed in the following databases: Web of Science, Scopus, and PubMed. The conducted literature search covered studies published between 2012 and 2020, without restrictions on language. The STROBE and NOS tools were used for quality assessment of the included studies.ResultsSixteen articles were included in the review. In total, 200,041 teeth were examined. On average, 6.3% of teeth had AP, and 7.4% had NSRCT. Forty-one percent of RCT teeth had AP, and 3.5% of untreated teeth had AP. Female patients were less prone to AP in endodontically treated teeth only, compared with male patients (P < .001). Variable stratification of age subgroups among included studies prevented us from conducting a meta-analysis. An increase in AP frequency was found in teeth with inadequate restorative and endodontic treatment (P < .001 and P < .001, respectively). Because of high heterogeneity, these results should be taken with caution.ConclusionsThere is an increased AP prevalence in the adult general population compared with data from 2012 (6.3% versus 5.4%) in both endodontically treated (41.3% versus 35.9%) and untreated teeth (3.5% versus 2.1%). In addition, AP developed less frequently in female patients with endodontically treated teeth and in teeth with inadequate compared with adequate restorative and endodontic treatment. |
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| Keywords: | Conventional nonsurgical root canal treatment epidemiology meta-analysis periapical periodontitis population prevalence systematic review |
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