Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial |
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| Affiliation: | 1. Retina-Vitreous Associates Medical Group, Beverly Hills, California;2. Apellis Pharmaceuticals, Inc, Waltham, Massachusetts;3. Vitreoretinal Consultants, Methodist Hospital, Houston, Texas;4. Ophthalmic Consultants of Boston, Boston, Massachusetts;5. Retina Consultants of Houston, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas;6. Retina Associates of Cleveland, Cleveland, Ohio;7. Black Hills Regional Eye Institute, Rapid City, Iowa;8. Institute of Human Genetics, University of Regensburg, Regensburg, Germany;9. Karolinska Institutet, Stockholm, Sweden;10. University of Cologne, Cologne, Germany;11. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida;12. Retina-Vitreous Associates Medical Group, Los Angeles, California;13. Vitreous Retina Macula Consultants of New York, New York;14. New York University School of Medicine, New York, New York |
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| Abstract: | |
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| Keywords: | AMD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0015" }," $$" :[{" #name" :" text" ," _" :" age-related macular degeneration BCVA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" best-corrected visual acuity CI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" confidence interval CNV" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" choroidal neovascularization EOM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" every-other-month FA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" fluorescein angiography GA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" geographic atrophy LL-BCVA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" low-luminance best-corrected visual acuity LL-VD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" low-luminance visual acuity deficit SE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" standard error TEAE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" treatment emergent adverse event VEGF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" vascular endothelial growth factor |
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