CT/MRI图像融合技术在鼻咽癌放疗靶区勾画中的应用价值

目的：探讨 CT/MRI融合技术在鼻咽癌放疗靶区勾画中的应用价值。方法对50例经病理证实的鼻咽癌患者进行调强放疗，分别在CT及CT/MRI融合图像下勾画鼻咽癌肿瘤靶区，比较CT组和CT/MRI组勾画的靶区体积的差异性。结果 CT组和CT/MRI组勾画的平均靶区体积分别为（29.18±19.12） cm^3和（33.57±20.63） cm^3，两组对比有显著性差异（P〈0.05）。在T1、T2、T3期中，两组体积对比差异明显（P〈0.05）；在T4期中，两组体积对比差异不明显（P〉0.05）。结论 CT/MRI融合技术结合CT和MRI两种不同成像技术的优势，有助于进一步提高鼻咽癌放疗靶区勾画的精确性。

Application Value of CT/MRI Image Fusion Technique in the Delineating of Target Area for Radiotherapy of Nasal Pharyngeal Cancer

Objective To explore the clinical value of CT/MRI image fusion technique in the delineating of gross tumor volume in intensity-modulated radiotherapy for nasal pharyngeal cancer （NPC）.Methods 50 patients confirmed as NPC by pathology were treated with intensity-modulated radiotherapy. The gross tumor volumes （GTVs） were delineated under CT images and CT/MRI fusion images respectively. Then the differences of GTVs between CT group and CT/MRI group were compared.Results The average GTVs of CT group and CT/MRI group were （29.18±19.12） cm^3 and （33.57±20.63） cm^3 respectively, and the differences were signiifcant （P〈0.05）. Comparing to the T stage, the two groups had obvious differences of GTVs on T1, T2 and T3 stage （P〈0.05）, but not obvious on T4 stage （P〉0.05）. Conclusion CT/MRI image fusion technology which combines CT and MRI, is helpful to improve the accuracy of delineating gross tumor volume in radiotherapy for NPC.