对米非司酮合并前列腺素终止早孕监护措施的探讨

我们对129例早孕患者应用米非司酮合并前列腺素终止妊娠并采用尿hCG 半定量测定,B 型超声检查及绒毛、蜕膜组织病理检查作为监护方法。结果表明在药流d15,出血在15d 内完全流产者中有70%尿hCG 滴度呈正常水平(<312mIU/ml)。而药流d15尿hCG 滴度≥1250mIU/ml 者,可能为不完全流产或完全流产但出血时间延长。B 型超声检查对诊断子宫出血时间长短有一定价值。绒毛蜕膜组织坏死程度则并非确定出血时间长短的唯一因素。

Clinical Surveillance of Mifepristone in Combination with Prostaglandin Analogue for Termination of Early Pregnancy

Clinical trial on Mifepristone in combination with Prostaglandin analogue for terminatiin of early pregnancy(129 cases)was conducted and the methods including the half quantitative test of urinary human Chorionic Gonadotropin(hCG),Ultrasound monitoring and pathologicexamination of the tissue of chorion and decidua were used as clinical surveillance.The results showed that the titer of urinary hCG level during the period of 15 days of thestudy was normal in 35 out of 50 cases(70%)of complete abortion with bleeding continuedwithin 15 days,but in the subjects with incomplete abortion urinary hCG levels continued torise(1250 mIU/ml)and bleeding prolonged in complete abortion.The examination by B modeUltrasound showed specific singnificance for duration of bleeding.In addition,it seemed that the degree of decidual necrosis was not a dependent factor foruterine bleeding to be lasted.