Bone Remodeling Interaction with Magnesium Alloy Implants Studied by SEM and EDX |
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| Authors: | Alexey Drobyshev Alexander Komissarov Nikolay Redko Zaira Gurganchova Eugene S. Statnik Viacheslav Bazhenov Iuliia Sadykova Andrey Miterev Igor Romanenko Oleg Yanushevich |
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| Affiliation: | 1.Laboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia;2.Laboratory of Hybrid Nanostructured Materials, National University of Science and Technology “MISiS”, 119049 Moscow, Russia;3.HSM Laboratory, Center for Energy Science and Technology, Skoltech, 121205 Moscow, Russia;4.Casting Department, National University of Science and Technology “MISiS”, 119049 Moscow, Russia |
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| Abstract: | The development direction of bioresorbable fixing structures is currently very relevant because it corresponds to the priority areas in worldwide biotechnology development. Magnesium (Mg)-based alloys are gaining high levels of attention due to their promising potential use as the basis for fixating structures. These alloys can be an alternative to non-degradable metal implants in orthopedics, maxillofacial surgery, neurosurgery, and veterinary medicine. In our study, we formulated a Mg-2Zn-2Ga alloy, prepared pins, and analyzed their biodegradation level based on SEM (scanning electron microscopy) and EDX (energy-dispersive X-ray analysis) after carrying out an experimental study on rats. We assessed the resorption parameters 1, 3, and 6 months after surgery. In general, the biodegradation process was characterized by the systematic development of newly formed bone tissue. Our results showed that Mg-2Zn-2Ga magnesium alloys are suitable for clinical applications. |
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| Keywords: | bioresorption magnesium alloys bioresorbable materials |
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