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Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility |
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| Authors: | Anthony M.-H. Ho Peter W. Dion Calvin S.H. Ng Lester A.H. Critchley Chi Wai Cheung |
| Affiliation: | a Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong b Department of Anaesthesia, St. Catharines General Hospital, St. Catharines, Ontario, Canada c Department of Accident and Emergency Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong d Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong e Department of Anaesthesiology, The University of Hong Kong, Hong Kong |
| Abstract: | During trauma resuscitation involving massive transfusion, the best fresh-frozen plasma to packed red blood cells ratio is unknown. No randomised controlled trial (RCT) is available on this subject, although there are plenty of observational studies suggesting that the ratio should be about 1:1. This ratio also makes more physiological sense, and we suggest that in patients with massive and ongoing bleeding, it is a sensible strategy with which to start resuscitation. |
| Keywords: | Coagulopathy Fresh-frozen plasma Red blood cells Transfusion Trauma |
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