Asymptomatic Chlamydia trachomatis infections in teenage males |
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| Institution: | 1. From the Division of Adolescent Medicine, Childrens Hospital of Los Angeles USA;2. From the Los Angeles County Central Juvenile Hall USA;1. Institute of Social and Preventive Medicine, University of Bern, Bern CH-3012, Switzerland;2. Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia;3. SOA AIDS Netherlands, Amsterdam, Netherlands;4. Department of General Practice/Family Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands;1. Centre for Youth Substance Abuse Research, The University of Queensland, K Floor, Mental Health Centre, Royal Brisbane and Women''s Hospital, Herston, Queensland 4029, Australia;2. School of Applied Psychology, Griffith University, Mt. Gravatt Campus, 176 Messines Ridge Road, Queensland 4111, Australia;3. Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, Queensland 4059, Australia;4. Faculty of Health, Queensland University of Technology, Victoria Park Road, Kelvin Grove, Queensland 4059, Australia;5. Discipline of Psychiatry, Faculty of Medicine, The University of Queensland, K Floor, Mental Health Centre, Royal Brisbane and Women''s Hospital, Herston, Queensland 4029, Australia;1. Materials Convergence and Design R&D Center, Korea Automotive Technology Institute, South Korea;2. Department of Materials Science and Engineering, Yonsei University, South Korea;3. School of Advanced Materials Engineering, Kookmin University, South Korea;4. V.A. Belyi Metal-Polymer Research Institute, Belarussian Academy of Sciences, Belarus;1. Larsen and Toubro Construction, Andheri, Mumbai, Maharashtra 400 093, India;2. Department of Civil Engineering, Indian Institute of Technology Tirupati, Andhra Pradesh, India;1. National Institute for Health Research Health Protection Research Unit in Modelling Methodology and Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, UK;2. Modelling and Economics Unit, National Infection Service, Public Health England, London, UK |
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| Abstract: | This study examined the prevalence of Chlamydia trachomatis infections of the urethra in asymptomatic teenage males in a juvenile detention setting. Gonorrhea cultures, chlamydia smears using the direct immunofluorescent antibody (DFA) technique, and 15–20 ml of a first-catch urine (FCU) sample were obtained. Of the 227 adolescent males screened, 205 had experienced sexual intercourse. Twenty-seven (13.2%) of the sexually active adolescents had positive DFA smears for C. trachomatis. Three (1.5%) had positive Neisseria gonorrhoeae cultures. A urine leukocyte count of greater than 10 per high-power field gave a 91% specificity but only a 26% sensitivity for a positive DFA. The high prevalence of chlamydia in this population and the relative low cost of the DFA screen for chlamydia make this a useful procedure for discovering unsuspected disease, particularly in a high-risk population. The FCU screen for leukocytec was of limited value in identifying asymptomatic infection. |
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