Complete Nucleotide Sequence Analysis of a Western Pacific Dengue-1 Virus Strain |
| |
| Authors: | Puri Beena Nelson William Porter Kevin R. Henchal Erik A. Hayes Curtis G. |
| |
| Affiliation: | (1) Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland, 20889-5607;(2) Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland, 21702-5011 |
| |
| Abstract: | We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively. This revised version was published online in July 2006 with corrections to the Cover Date. |
| |
| Keywords: | dengue-1 Western Pacific virus Flavivirus nucleotide sequence |
| 本文献已被 SpringerLink 等数据库收录！ |
|
