Beta-papillomavirus infection and skin cancer |
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Authors: | Bouwes Bavinck Jan Nico Plasmeijer Elsemieke I Feltkamp Mariet C W |
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Institution: | Department of Dermatology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands. j.n.bouwes_bavinck@lumc.nl |
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Abstract: | The development of highly sensitive PCR techniques and multiplex bead-based Luminex platforms has accelerated the search for a specific role of human papilloma viruses in the development of squamous cell carcinoma. Human papillomaviruses are most likely indirectly involved in this process by facilitating UV-related carcinogenesis via preventing UV-induced apoptosis or impairing DNA repair, but other mechanisms are also possible. |
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