| 桂竹糖芥强心苷G对Na+,K+-ATP酶的抑制作用 |
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| 引用本文： | 张晓丹,季宇彬,马瑛,乔国芬,孔琪.桂竹糖芥强心苷G对Na+,K+-ATP酶的抑制作用[J].中草药,1999,30(10):758-760. |
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| 作者姓名： | 张晓丹 季宇彬 马瑛 乔国芬 孔琪 |
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| 作者单位： | 黑龙江商学院中药系!哈尔滨150076(张晓丹，季宇彬，孔琪)，黑龙江省计划生育药具站(马瑛)，哈尔滨医科大学药理教研室(乔国芬) |
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| 基金项目： | 黑龙江省科委自然科学基金 |
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| 摘 要： | 对照哇巴因观察糖芥强心苷Ｇ对大鼠心肌ＡＴＰ酶活性的影响。结果表明糖芥苷Ｇ体外显著抑制心肌Ｎａ＾＋、Ｋ＾＋－ＡＴＰ酶，并呈浓度依赖性，而ＡＴＰ对糖芥苷Ｇ的作用几无影响。
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| 关 键 词： | 桂竹糖芥 强心苷G 钠离子 钾离子 ATP酶 |
| 收稿时间： | 1999/5/17 0:00:00 |
Inhibitory Action of Cheiranthoside G on Na+,K+-ATPase |
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| Zhang Xiaodan,Ji Yubin,Ma Ying.Inhibitory Action of Cheiranthoside G on Na+,K+-ATPase[J].Chinese Traditional and Herbal Drugs,1999,30(10):758-760. |
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| Authors: | Zhang Xiaodan Ji Yubin Ma Ying |
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| Institution: | Zhang Xiaodan, Ji Yubin, Ma Ying, et al. |
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| Abstract: | The mechanism of inhibition of Na~ , K~ -ATPase by cheiranthoside G was studied. Characteristics of its inhibitory action of Na~ , K~ -ATPase were compared with those of ouahain. Results indicated that cheiranthoside G was a noncompetitive inhibitor with respect to Na ,K , and the effect was dose dependent. ATP was without effect on Na , K -ATPase inhibition by cheiranthoside G' |
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| Keywords: | cheiranthoside G Na~ K~ -ATPase |
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