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正交试验法优选苓桂术甘汤的提取工艺
引用本文:黄金玲,王慧慧,陈慧芳,吴德玲,刘先华,王桐生,侯晓燕.正交试验法优选苓桂术甘汤的提取工艺[J].安徽中医学院学报,2011,30(6):65-68.
作者姓名:黄金玲  王慧慧  陈慧芳  吴德玲  刘先华  王桐生  侯晓燕
作者单位:1. 安徽中医学院中西医结合临床学院,安徽,合肥,230038
2. 安徽中医学院药学院,安徽,合肥,230031
3. 安徽中医学院科研实验中心,安徽,合肥,230038
基金项目:国家自然科学基金,安徽省2010年度科研计划项目
摘    要:目的优选苓桂术甘汤的水提取工艺。方法采用正交试验,考察加水量、煎煮时间、煎煮次数对苓桂术甘汤中肉桂酸含量及干膏得率的影响。结果优选出的最佳提取工艺为:加10倍量的水,提取2次,每次1h。结论该提取工艺由于稳定、合理、可行,可用于苓桂术甘汤中有效成分的提取。

关 键 词:苓桂术甘汤  正交试验  提取工艺  肉桂酸

Optimization of Extraction Technology for Linggui Zhugan Decoction by Orthogonal Test
HUANG Jin-ling,WANG Hui-hui,CHEN Hui-fang,WU De-ling,LIU Xian-hua,WANG Tong-sheng,HOU Xiao-yan.Optimization of Extraction Technology for Linggui Zhugan Decoction by Orthogonal Test[J].Journal of Anhui Traditional Chinese Medical College,2011,30(6):65-68.
Authors:HUANG Jin-ling  WANG Hui-hui  CHEN Hui-fang  WU De-ling  LIU Xian-hua  WANG Tong-sheng  HOU Xiao-yan
Institution:(1.Clinical School of Integrative Traditional Chinese and Western Medicine,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230038,China;2.Department of Pharmacy,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China;3.Department of Science and Technology,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230038,China)
Abstract:Objective To optimize the extraction technology for Linggui Zhugan Decoction,a famous classical Recipe in Treatise on Febrile Diseases composed of Poria cocos,Ramulus Cinnamomi,Glycyrrhiza uralensis,and Rhizoma Atractylodis Macrocephalae.Methods An orthogonal test was employed to observe the influences of the amount of water,extracting time,and extracting times on the contents of cinnamic acid,and the yield of dry extracts of Linggui Zhugan Decoction.Results The optimized extracting process was as follows:Adding 10 times of water,extracting for 2 times,and extracting for 1 h per time.Conclusion The optimized process can be used for extracting active components from Linggui Zhuigan Decoction because of its being stable,reasonable,and feasible.
Keywords:Linggui Zhugan Decoction  orthogonal test  extracting technology  cinnamic acid
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