| IL-23R基因多态性与汉族人寻常型银屑病表型相关性研究 |
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| 引用本文： | 李珊珊,邵莉梅,张丽君,姜新,崔婧,左先波,崔勇,孙良丹,杨森,刘建军,张学军.IL-23R基因多态性与汉族人寻常型银屑病表型相关性研究[J].安徽医科大学学报,2011,46(11):1168-1171. |
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| 作者姓名： | 李珊珊 邵莉梅 张丽君 姜新 崔婧 左先波 崔勇 孙良丹 杨森 刘建军 张学军 |
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| 作者单位： | 1. 安徽医科大学第一附属医院皮肤病研究所,皮肤科,合肥,230022;皮肤病学国家重点实验室培育基地,合肥,230032;安徽医科大学皮肤病与性病学系,合肥,230032
2. 安徽医科大学第一附属医院皮肤病研究所,皮肤科,合肥,230022;皮肤病学国家重点实验室培育基地,合肥,230032 |
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| 摘 要： | 目的 探讨IL-23R基因多态性rs3762318位点与汉族人寻常型银屑病临床表型(发病年龄、家族史及皮损类型)的相关性.方法 选取2 883例银屑病患者和6 180例正常对照的rs3762318位点基因分型资料和临床资料,采用χ2检验比较各组间基因型和等位基因频率的分布.结果 病例组与对照组间rs3762318位点基...
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| 关 键 词： | 寻常型银屑病 IL-23R基因 多态性 表型 |
Correlation of IL-23R gene polymorphism with some clinical features of psoriasis vulgaris in Chinese Han population |
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| Li Shanshan,,Shao Limei,Zhang Lijun,et al.Correlation of IL-23R gene polymorphism with some clinical features of psoriasis vulgaris in Chinese Han population[J].Acta Universitis Medicinalis Anhui,2011,46(11):1168-1171. |
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| Authors: | Li Shanshan Shao Limei Zhang Lijun |
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| Institution: | Li Shanshan1,2,3,Shao Limei1,Zhang Lijun1,et al(1Institute of Dermatology and Dept of Dermatology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,2 State Key Laboratory Incubation Base of Dermatology,Ministry of National Science and Technology,Hefei 230032,3 Dept of Dermatology and Venereology,Anhui Medical University,Hefei 230032) |
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| Abstract: | Objective To investigate the potential association of IL-23R gene rs3762318 polymorphism and some phenotypes of psoriasis vulgaris in Chinese Han population.Methods Genotyping data and clinical data of 2 883 cases and 6 180 controls from our previous study were selected.Chi square test was used for comparing genotype or allele frequency distribution among the groups.Results The genotypic and allelic frequencies of rs3762318 in IL23R gene were statistical significance between the cases and the controls(Pgeno... |
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| Keywords: | psoriasis vulgaris IL-23R gene polymorphism phenotype |
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