179例妊娠期肝内胆汁淤积症的临床分析

目的探讨妊娠期肝内胆汁淤积症的妊娠结局、产科并发症与胆汁酸、肝功能的相关性。方法总结分析该院179例ICP患者,根据其病情将ICP分为轻度与重度两组;比较两组的妊娠结局及产科并发症。结果轻度ICP 83例,重度ICP 96例,重度ICP的胎膜早破、胎儿窘迫、早产、羊水粪染、剖宫产等的发生率较轻度ICP的几率高,差异有统计学意义。结论 ICP要早发现、早治疗;重症ICP妊娠结局异常几率明显增加,要加强孕期监护,适时终止妊娠。

Clinical analysis on 179cases of intrahepatic cholestasis of pregnancy

Aim To explore the relativity of level of the bile acid and liver function compare to the outcome of pregnancy and Pregnancy complications on pregnant women in the patients of intrahepatic cholestasis of pregnancy（ICP）.Methods The clinical data of 179 pregnant womem in the patients of ICP,according to the condition is divided into a light degree of ICP with heavy degree 2 group;Compare two groups of gestation final outcomes and obstetrics complications.Result Light degree ICP is 83,heavy degree ICP is 96,in the heavy degree ICP group the incidence rate of premature rupture of membrane,fetal distress,premature delivery,amniotic fluid muck dye and Caesarean section is higher,significant difference was found between the two groups（P〈0.05）.Conclusion ICP wants and discovers to cure early and early;The advanced case ICP gestation final outcome unusually several rates obviously increase,strengthen maternal care and terminate gestation in good time.