| HPLC法测康妇灵滴丸中盐酸小檗碱的含量 |
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| 引用本文： | 李平.HPLC法测康妇灵滴丸中盐酸小檗碱的含量[J].安徽医药,2011,15(12):1518-1519. |
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| 作者姓名： | 李平 |
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| 作者单位： | 南京医药合肥天星有限公司,安徽,合肥,230061 |
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| 摘 要： | 目的建立用高效液相色谱法测定康妇灵滴丸中盐酸小檗碱含量的方法。方法采用HPLC法,AlltimaC18柱(4.6 mm×250 mm),流动相:0.1%磷酸溶液-乙腈(50∶50),流速:1.0 ml·min-1,检测波长:265 nm,柱温:30℃。结果盐酸小檗碱浓度范围在10.08～100.8 mg·L-1之间峰面积(S)与浓度(C)线性关系良好。结论该法可用于康妇灵滴丸的质量控制。
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| 关 键 词： | HPLC 康妇灵滴丸 盐酸小檗碱 |
Determination of Berberine hydrochloride in Kangfuling dropping pills by HPLC |
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| LI Ping.Determination of Berberine hydrochloride in Kangfuling dropping pills by HPLC[J].Anhui Medical and Pharmaceutical Journal,2011,15(12):1518-1519. |
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| Authors: | LI Ping |
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| Institution: | LI Ping(Nanjing Medical Hefei Tianxing Co,Ltd,Hefei 230061) |
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| Abstract: | Aim To establish a method for the determination of berberine hydrochloride in Kangfuling dropping pills by HPLC.Methods An HPLC method was established.The chromatographic column was Alltima C18（4.6 mm×250 mm）.The mobile phase was 0.1% Phosphoric： acid-Acetonitrile（50∶ 50） with the flow rate of 1.0 ml·min^-1,and the detection wavelength was 265nm.The column temperature was 30℃.Results The linear range for berberine hydrochloride 10.08-100.8 mg·L^-1 respectively.Conclusion The method can be used for quality control of Kangfuling dropping pills. |
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| Keywords: | HPLC Kangfuling dropping pills berberine hydrochloride |
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