胱抑素C在急性冠脉综合征中的临床价值

目的:探讨胱抑素C(cys C)在急性冠脉综合征(ACS)中的临床价值。方法:检测121例急性冠脉综合征患者血清胱抑素C水平,其中,急性心肌梗死(AMI)34例;不稳定心绞痛(UAP)48例;稳定性心绞痛(AP)39例,并比较13例ACS患者治疗前、后的胱抑素C浓度的变化。同时,选择20例非急性冠脉综合征患者做对照研究。结果:AMI组、UAP组胱抑素C水平显著高于对照组(P<0.001),AP组与对照组比较无统计学意义(P>0.05);AMI组显著高于AP组(P<0.001),但与UAP组比较无统计学意义(P>0.05);13例ACS患者治疗前、后的胱抑素C浓度比较有统计学意义(P<0.01)。结论:监测ACS患者血清胱抑素C水平对急性冠脉综合征的临床诊断、疗效评价和预后评估具有一定的价值。

The clinical value of cystatin C in acute Coronary Syndrome

Objective：To explore the clinical value of cystatin C in acute coronary syndrome.Methods： Detect the levels of serum cystatin C in 121patients with acute coronary syndrome,among them,AMI 34cases,UAP 48cases,AP 39cases.To compare the changes of serum cystatin C in 13 patients with ACS who accept the treatment or not.And the 20 patients who without ACS were chosen as control group.Results： The level of cystatin C in serum was remarkable higher in AMI and UAP than control group（P〈0.001）,and it in AMI was higher than in AP either.In addition it was significant decrease in 13 ACS when they were treated（P〈0.01）.Conclusion： There was certain value of detecting cystatin C in ACS patient’s serum in clinical diagnosis,response evaluation,prognosis assessment 更多