颅痉宁方治疗三叉神经痛的临床研究

目的观察颅痉宁方治疗三叉神经痛的临床疗效。方法将58例三叉神经痛患者按入选顺序分为治疗组与对照组,治疗组给予卡马西平加颅痉宁方治疗,对照组仅予卡马西平治疗。观察各组简化McGill疼痛量表评分及肌电图瞬目反射各指标改善情况。结果简化McGill疼痛量表评分方面,治疗组治疗后PRI感觉分、总分低于对照组,且有统计学意义(P<0.05),简化McGill疼痛量表评分各项治疗前后差值比较,治疗组优于对照组,结果有统计学意义(P<0.05),治疗组对疼痛缓解明显优于对照组。瞬目反射方面,治疗组与对照组治疗后受累侧R1、R2较治疗前相比均明显改善,治疗组改善程度优于对照组,差异有显著性(P<0.05)。结论颅痉宁方加用卡马西平治疗三叉神经痛,较单用卡马西平具有更好的临床疗效。

Trigeminal neuralgia treatment with lujingningfang

Aim To observe the clinical effects of trigeminal neuralgia treatment with lujingningfang.Methods First,Fifty-eight patients were divided into treatment group and control group according to the selecting order.Patients in treatment group were treated with carbamazepine and lujingningfang.Patients in control group were treated only with carbamazepine.Then,the scores of Simplified McGill Table,change of EMG and blink reflex indexes were observeds.Results As for Scores of Simplified McGill Table,PRI feeling score and total score of treatment group were lower than those of control group and of statistical significance（P〈0.05）.The comparative result of scores difference as well as the result of pain relief of treatment group was better than control group and of statistical significance（P〈0.05）.As for blink reflex,significant improvement was shown in R1 and R2 of involvement side in both groups.However,better improvement was shown in treatment group with significant difference（P〈0.05）.Conclusion Using lujingningfang with carbamazepine to treat trigeminal neuralgia has better clinical curative effect than using carbamazepine only.