| 基因芯片技术在疟疾研究中的应用 |
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| 引用本文： | 张国庆,汤林华. 基因芯片技术在疟疾研究中的应用[J]. 国际医学寄生虫病杂志, 2007, 34(4): 180-183 |
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| 作者姓名： | 张国庆 汤林华 |
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| 作者单位： | 中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海,200025 |
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| 摘 要： | 20世纪80年代末发展起来的基因芯片技术在生命科学众多研究领域中已显示出强大优势。恶性疟原虫和冈比亚按蚊全基因组测序完成后，该技术开始逐步应用于疟原虫、传疟按蚊以及疟疾动物模型的研究。该文概述了基因芯片的基本原理及其在疟疾研究中的应用。
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| 关 键 词： | 基因芯片 疟疾 疟原虫 按蚊 动物模型 |
| 修稿时间： | 2006-12-30 |
The application of gene chip technology in malaria research |
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| ZHANG Guo-qing,TANG Lin-hua. The application of gene chip technology in malaria research[J]. International JOurnal of Medical Parasitic Diseases, 2007, 34(4): 180-183 |
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| Authors: | ZHANG Guo-qing TANG Lin-hua |
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| Affiliation: | Department of Malaria, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Laboratory of Parasite and Vector Biology, Ministry of Public Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China |
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| Abstract: | Gene chip technology, developed in the late 1980s, has been demonstrating great power on various areas of life science. This technology has been gradually applied in the research of Plasmodium, Anopheles and malaria animal models since the accomplishment of whole genome sequencing of Plasmodium falciparum and Anopheles gambiae. This review summarises the basic principle of DNA micorarray and its application in malaria research. |
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| Keywords: | Gene chip Malaria Plasmodium Anopheles Animal model |
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