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Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit |
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| Authors: | Yunxiao Zhang Wan-Jin Lu David P. Bulkley Jiahao Liang Arthur Ralko Shuo Han Kelsey J. Roberts Anping Li Wonhwa Cho Yifan Cheng Aashish Manglik Philip A. Beachy |
| Abstract: | |
| Keywords: | hedgehog cryo-EM nanobody Patched transporter |