本院ICU病区葡萄球菌感染状况及分布现状

目的了解我院重症监护病区(ICU)的葡萄球菌的感染状况及分布,以指导临床预防及治疗用药。方法对86株分离自ICU病区葡萄球菌标本分布和药物敏感性进行检测分析。结果葡萄球菌呼吸道感染占64%,居首位。86株葡萄球菌中耐甲氧西林的金黄色葡萄球菌(MRSA)34株,耐甲氧西林凝固酶阴性的葡萄球菌(MRCNS)43株,甲氧西林敏感凝固酶阴性的葡萄球菌(HSCNS)9株,无甲氧西林敏感的金黄色葡萄球菌(MSSA)。MRS表现为多重耐药。结论葡萄球菌特别是MRS的感染在重症监护病区医院获得性感染中占较重要的地位。临床应严格掌握抗菌药物应用指征,预防MRS的产生。

Staphylococcus Infection and distribution in our local ICU

Objectives To provide the clinical precautionary advice and dosage guidance by analyzing the infection and distribution of the acquired staphylococcus from the intensive care unit (ICU). Methods Analystic measurement testing on staphylococcus distribution and drug resistance was done on 86 clinical staphylococcus samples submitted from ICU. Results Respiratory tract infection rate was 64%, being the major one. Out of the total 86 samples, we found 34 with methicillin-resistant staphylococcus aureus (MRSA), 43 with methicillin-resistant coagulase-negative staphylococci (MRCNS), and 9 with methicillin-susceptible coagulase-negative staphylococci (MSCNS). Methicillin-susceptible staphylococcus aureus (MSSA) was not found during the testing. MRS was identified to have multi-drug resistance. Conclusion Staphylococcus infection, especially the infection with MRS, is remarkable among the acquired infections in ICU. When we decide the clinical antibiotic therapy for the patient, it is recommended that we have strict supervision on its clinical application to avoid possible MRS infection.