ER-D5 antigen immune radiometric assay in breast cancer research |
| |
| Authors: | G B Nardelli |
| |
| Affiliation: | Institute of Obstetrics and Gynaecology, University of Padua, Italy. |
| |
| Abstract: | A trial of 185 breast cancer tissues has been developed to characterize receptor negative tumors. We observed the ER-D5-Ag availability to recognize the hormone sensitivity inside the receptor-negative patient groups. In Pre-M ER--ve patients, we observed 26.9%-29.4% of D5+ve cases and in PgR--ve 50% of D5+ve cases. In Post-M ER--ve patients, we observed 31.2%-36.5% of D5+ve cases and in PgR--ve 53.2% of D5+ve cases. The reproducibility of our results suggests the relevance of an additional investigation to characterize the hormonal sensitivity of receptor-negative breast cancer tissues. |
| |
| Keywords: | |
|
|
