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Hormonal influence on experimental infections by a toxic shock strain of Staphylococcus aureus. |
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| Authors: | G K Best T O Abney J M Kling J J Kirkland and D F Scott |
| Abstract: | Subcutaneous infection chambers in rabbits were infected with a strain of Staphylococcus aureus isolated from a patient with toxic shock syndrome. Estrogens (mestranol and 17-beta-estradiol) protected male rabbits and prolonged survival. Neither androgens (testosterone and dihydrotestosterone) nor progesterone affected the susceptibility of intact or ovarihysterectomized female rabbits. |
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