| 皮肤屏障功能与其神经鞘酯类关系的探讨 |
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| 引用本文： | 李洪 任道凤. 皮肤屏障功能与其神经鞘酯类关系的探讨[J]. 皮肤病与性病, 1994, 16(4): 1-5 |
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| 作者姓名： | 李洪 任道凤 |
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| 作者单位： | 云南省职业病防治研究所，上海医科大学公共卫生学院劳卫教研室 |
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| 摘 要： | 利用新生大鼠皮肤的培养，研究皮肤屏障功能与其神经鞘酯类的关系．结果发现皮肤屏障功能在培养后的第１天略有降低，以后恢复正常．第１０天起明显下降；皮肤的神经鞘酯类化合物随着培养时间的延长，乙酰神经酰胺，乙酰葡萄糖神经酰胺趋向降低，糖鞘酯呈显著下降，神经既胺趋向增高。结果提示皮肤屏障功能与神经鞘酯类的代谢有一定关系。
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| 关 键 词： | 皮肤，屏障功能，神经鞘醋 |
The research of relatonship between the she permeability barrier and sphingolipid |
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| Li Hong et al. The research of relatonship between the she permeability barrier and sphingolipid[J]. Journal of Dermatology and Venereology, 1994, 16(4): 1-5 |
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| Authors: | Li Hong et al |
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| Affiliation: | Institute of Occupational Disease of Yunnan |
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| Abstract: | To use the l1ew born rats skin to study the relationship between the skin permeability barrier and sphingolipid.It was found that the skin permeability barrier function decreased a Iittle on tl e first ciiltured da y,then it iecover ed norma1.On the 1 0 day,the ba rrier function significantly decreased,the Acy ceramide,Acyglucoseceramide,Glycospinolipid:also decreased, but the Ceramide had increased tendenay.The result showed that there is relationship between the skin permeability barrier and sphingolipid. |
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| Keywords: | skin barrier function sphingolipid |
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