以医院为基础的羊水粪染流行病学分析

目的了解羊水粪染产前和产时相对因素的流行病学情况。方法采用队列研究方法,将6206例单胎妊娠分娩的围产期情况,分成羊水粪染和羊水正常组进行统计学分析。结果羊水粪染的发生率为16.4%。母体的内科合并症,在羊水粪染组和正常羊水组均无明显差异。母体产次、妊娠周数≥42周和体重较大胎儿所占比例,羊水粪染组明显高于正常羊水组(P<0.001)。羊水粪染组的新生儿出生评分低于正常羊水组(P=0.001)。羊水粪染组的死产率、低体重儿比例和新生儿在出生4h后转入儿科病房比例均高于正常羊水组(P<0.001)。结论羊水粪染相关因素有母体产次、妊娠周数≥42周和胎儿体重较大,与母体的内科合并症无明显关系。羊水粪染的新生儿患病率较高。羊水粪染是一个重要的预测产科结局的临床参数。

The epidemiology of meconium stained amniotic fluid on hospital basis

OBJECTIVE: To explore the epidemiology of meconium stained amniotic fluid pero-delivery. METHODS: 6,206 one-fetal delivery cases were divided into meconium stained amniotic fluid and normal amniotic fluid groups. Statistics were analysed on two groups using Cohort study. RESULTS: Incidence of meconium stained amniotic fluid was 16.4%. There was no significant difference on maternal medical complication between two groups. The percentage of parity, gestational week > or = 42 weeks and big birth weight were higher in meconium stained amniotic fluid group than that in normal amniotic fluid group (P < 0.001). The average Apgar score in meconium stained amniotic fluid group was lower than that in normal amniotic fluid group (P = 0.001). The percentage of stillbirth, low birth weight and transferred newborn care unit in meconium stained amniotic fluid group were higher than that in normal amniotic fluid group (P < 0.001). CONCLUSIONS: The relative factors on meconium stained amniotic fluid were maternal parity, gestational weeks > or = 42 weeks and big birth weight. No correlation between meconium stained amniotic fluid and maternal medical complication. Morbidity of newborn baby was higher in meconium stained amniotic fluid. Meconium stained amniotic fluid is a important clinical factor on evaluating pregnancy outcome.