子宫肌瘤剔除术后米非司酮预防肌瘤复发的临床分析

目的：探讨米非司酮预防子宫肌瘤剔除术后子宫肌瘤复发的临床效果。方法：70例子宫肌瘤患者随机分成单独手术组和联合治疗组,两组均行腹腔镜子宫肌瘤剔除术,联合治疗组患者术后接受米非司酮治疗。分析两组患者12个月时子宫肌瘤的复发情况,3个月和12个月血清雌二醇（E2）和孕激素水平。结果：3个月时联合治疗组血清雌二醇（E2）和孕激素明显低于单独手术组,而12个月时两组无明显差异,联合治疗组子宫肌瘤的复发率明显低于单独手术组。结论：子宫肌瘤剔除术后服用米非司酮可以有效地预防子宫肌瘤的复发。

Clinical research on prevention of mifepristone to recurrence of uterine fibroids after myomectomy

Objective：To evaluate the mifepristone＇ s prevention to recurrence of uterine fibroids after myomectomy.Methods：70 cases of uterine fibroids were randomly divided into surgery group and combined treatment group,both groups underwent laparoscopic myomectomy,the patients of the combined treatment group received postoperative treatment with mifepristone.All patients were analysis of recurrence in 12 months,the serum level of estradiol（E2） and progesterone hormone in 3 months and 12 months after surgery.Results：After 3 months,the serum level of estradiol（E2） and progesterone of the combined treatment group were significantly lower than that of the surgery group.After 12 months,there were no signifi cant difference between the two groups.Recurrence rate of the combined treatment group was significantly lower than that of the surgery group.Conclusion：Mifepristone may be effective in preventing the recurrence of uterine fibroids after myomectomy.