急性少量、中量饮酒对健康汉族人群共济运动及自主神经功能的影响

测量21例健康汉族自愿者少量、中量饮酒前后自主神经功能、血压、共济运动及血液中的酒精浓度，以探讨急性少量、中量饮酒对健康汉族人群共济运动及自主神经功能的影响。结果发现饮酒后心率明显增加．自主神经总功率明显降低；少量饮酒对卧位副交感神经功能有明显抑制作用，中量饮酒对副交感神经和交感神经功能均有明显抑制作用；少量饮酒后站立位的收缩压和舒张压及卧位的舒张压明显降低；中量饮酒后两种体位的收缩压和舒张压均明显降低；少量饮酒后有部分受试者出现共济失调，中量饮酒后共济失调程度加重；自主神经功能、血压及共济运动的变化程度与血液中的酒精浓度无显著相关性。结果表明少量、中量饮酒能引起部分受试者出现共济失调，并能抑制自主神经功能．影响心血管的调节能力，随着酒精摄入量的增加．抑制作用进一步加强，这些均不利于机体适应环境的急剧变化。

Acute Effects of Low and Moderate Doses of Alcohol on Coordinate Motor and Autonomic Nervous Function in a Group of Healthy Hans

The autonomic nervous function,blood pressure,coordinate motor and blood alcohol concentration(BAC) of twenty-one healthy Han volunteers were examined before and after alcohol intake.The purpose was to assess the acute effects of low and moderate doses of alcohol on their coordinate motor and autonomic nervous function.The results showed that after alcohol intake the subjects' heart rate increased and the total power value(TPV) decreased significantly.After the intake of alcohol at low dose,the parasympathetic nervous function of the subjects lying supoine was inhibited significantly.After the intake of alcohol at moderate dose,both the parasympathetic and the sympathetic nervous functions were inhibited.After the intake of alcohol at low dose,both the systolic pressure and the diastolic pressure of the subjects standing up-right were decreased and the diastolic pressure of those lying supine were also decreased.After the intake of alcohol at moderate dose,the systolic and diastolic pressures of the subjects,either lying supine or standing up-right,were decreased.Some subjects showed ataxia after the intake of alcohol at low dose,and some showed aggravated ataxia after intake of alcohol at moderate dose of alcohol.There was no relationship of BAC with the degree of changes in autonomic nervous function,blood pressure and ataxia.The results indicated that ataxia was induced to come on and the autonomic nervous function was inhibited in some subjects who had taken low and moderate doses of alcohol,and the cardiovascular regulation was affected too.These suggested that the increase of alcohol intake is adverse to human body's adaptation to the sharp change of circumstance.