国际胃癌新分期对我国临床应用的指导意义

第7版胃癌国际分期对T分期和N分期做出了重大调整,日本胃癌分期与UICC/AJCC分期实现了统一.日本胃癌诊治指南对临床关注的有关淋巴结清扫范围做出了明确规定.新版TNM分期由于采用了日韩的数据,因此,能更准确地预测标准淋巴结清扫术后患者的预后.对于是否需要切脾并清扫第10组淋巴结、全网膜囊切除的必要性、第13组和第14组淋巴结转移对预后的影响等问题,需要进一步的循证医学证据.D2淋巴结清扫已为东西方学者普遍接受.对特定病例,腹主动脉旁淋巴结清扫的意义有待进一步临床试验证实.国际胃癌分期项目将从全球23个国家收集数据,相信第8版国际胃癌分期将具有真正的国际化意义.

Clinical aspect of new international gastric cancer staging system

The 7th UICC/AJCC Gastric Cancer TNM Staging System includes major revisions of pT and pN classification. The Japanese Classification and UICC/AJCC TNM System have reached consistency in staging of gastric cancer. There are some new topics of lymphadeneetomy in the new guidelines. Tile new TNM system aceepts the database from Japan anti Korea and it will be more accurate to predict the prognosis of gastric cancer patients. The rationality of splenectomy, total bursectomy, dissection of No.13 and No.14 lymph nodes is still not ve clear and needs more evidences. D2 lymphadeneetomy is the recommended surgical approach both in Eastern and Western countries. The benefit of paraaortic lymphadenectmoy for selected patients needs furtherevidences as well. The international gastric cancer staging project will collect the data from 23 countries and the new staging system will be applicable worldwide.