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Intraincisional antibiotic in addition to systemic antibiotic treatment fails to reduce wound infection rates in contaminated abdominal surgery |
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| Authors: | Dr. Flemming Moesgaard M.D. Mogens Lykkegaard Nielsen M.D. Ph.D. Allan Hjortrup M.D. Peter Kjersgaard M.D. Carsten Sørensen M.D. Peter Nørgaard Larsen M.D. Steen Hoffmann M.D. |
| Affiliation: | (1) Department of Surgical Gastroenterology Rigshospitalet, University Hospital, Copenhagen;(2) Department of Surgery, Sundby Hospital, Copenhagen;(3) Department of Surgery, Frederikssund Hospital, Frederikssund, Denmark;(4) I Stoltenbergsgade, DK-1576 Copenhagen, Denmark |
| Abstract: | One hundred ninety patients with peritonitis at the time of abdominal surgery were allocated at random to systemic antibiotic treatment alone or systemic antibiotic treatment combined with topical application of antibiotics in the wound at the time of wound closure. The overall wound infection rate was 17 percent without significant difference between the two treatment groups (P>0.80). |
| Keywords: | Intraincisional antibiotics Wound sepsis |
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