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腔静脉滤器在老年下肢深静脉血栓患者治疗中的应用
引用本文:陈兵,俞恒锡,李建新,谷涌泉,郭连瑞,崔世军,杨盛家,佟铸,张建. 腔静脉滤器在老年下肢深静脉血栓患者治疗中的应用[J]. 中华老年心脑血管病杂志, 2010, 12(11). DOI: 10.3969/j.issn.1009-0126.2010.11.005
作者姓名:陈兵  俞恒锡  李建新  谷涌泉  郭连瑞  崔世军  杨盛家  佟铸  张建
作者单位:首都医科大学宜武医院血管外科,北京,100053
摘    要:目的探讨腔静脉滤器在老年下肢深静脉血栓患者治疗中的应用。方法选择77例急性下肢深静脉血栓患者,将年龄≥60岁的48例为老年组,年龄60岁的29例为非老年组,2组均置入腔静脉滤器,术后采用接触性导管溶栓23例,外周血管溶栓54例,以治疗3 d后患肢膝关节上15 cm周径较治疗前的变化判断疗效。结果全部患者顺利置入腔静脉滤器,技术成功率100%。术后无肺动脉栓塞发生。与治疗前比较,老年组和非老年组治疗后患肢膝关节上15 cm周径明显下降(P0.05),但2组治疗前后膝关节上15 cm周径变化差值无明显差异(P=0.324)。接触性导管溶栓较外周血管溶栓治疗效果更佳(P=0.000)。1例成功取出腔静脉滤器,13例次出现抗凝过度情况。结论腔静脉滤器及温和的溶栓治疗,可以有效防止老年患者肺动脉栓塞的发生,安全性高。

关 键 词:腔静脉滤器  静脉血栓形成  下肢  肺栓塞  血栓溶解疗法

Application of vena cava filter in elderly patients with lower extremity deep venous thrombosis
Abstract:Objective To evaluate the vena cava filter implantation therapy for deep venous thrombosis in elderly patients.Methods Seventy-seven patients were divided into two groups:senile group(48 cases) and non-senile group(29 cases).All received implantation of inferior vena cava filter(IVCF).Anti-coagulation and thrombolytic treatment were given.Results All vena cava filters were applied successfully and no pulmonary embolism occurred.The difference of treatment effect in two groups had no statistical significance (P = 0.324).Twenty-three patients receiving catheter-directed thrombolysis showed better outcomes than those receiving peripheral blood vessel thrombolysis (P = 0.000).IVCF was removed from 1 patient after treatment.Thirteen casetimes showed excessive anti-coagulation phenomenon.Conclutions The vena cava filter implantation and moderate thrombolysis treatment can prevent the occurrence of pulmonary embolism in elderly patients effectively and safely.
Keywords:vena cava filters  venous thrombosis  lower extremity  pulmonary embolism  thrombolytic therapy
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