富铬酵母降低高血脂作用的研究 |
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引用本文: | 田晓华,庞文贞.富铬酵母降低高血脂作用的研究[J].营养学报,1994,16(2):126-132. |
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作者姓名: | 田晓华 庞文贞 |
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摘 要: | 本文观察富铬酵母(合铬40mg/kg)对高脂血症患者63人,Ⅱ型糖尿病合并高脂血症患者82人及血脂正常的Ⅱ型糖尿病人35人血脂的作用。每日补充2.5g富铬酵母(相当于100μg酵母铬)3个月。以50例健康成人的有关指标作为对照。结果表明:a.63例高脂血症患者血请铬显著低于健康人(分别为3.58和5.27nmol/L),服用富铬酵母后,血清铬升高(由3.58升至6.10nmol/L)。高TC患者的TC和高TG患者的TG降低,分别为6.35与5.34mmol/L和3.05与2.24mmol/L,且LDL-C降低,HDL-C升高,与服药前比较均有显著性差异。降脂效果优于月见草油。合并Ⅱ型糖尿病的高脂血症患者服用富铬酵母后,血清Cr、TC、TG、LDL-C和HDL-C也有相似的变化,且有显著性差异。b.富铬酵母(少数人加服2.5~5mg优降糖辅助)治疗Ⅱ型糖尿病合并高脂血症患者,其降脂降糖效果优于单纯使用口服降糖药,且过氧化脂质较治疗前显著降低(由6.90降至5.51μmol/L)。血脂正常的Ⅱ型糖尿病人服用富铬酵母后除空腹血糖显著降低及HDL-C显著升高外,TC、TG及LDL-C均无明显变化。c.富铬酵母对高脂?
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关 键 词: | 富铬酵母,高脂血症,Ⅱ型糟尿病,血清铬,血硒,全血GSH-PX |
A STUDY ON THE ANTIHYPERLIPIDEMIC ACTION OF CHROMIUM -ENRICHED YEAST |
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Abstract: | ixty three hyperlipidemic, eighty two NIDDM
complicated with hyper-lipidemia and thirty fivc NIDDM patients with normal blood lipids were
given 100μg Cr daily in the form of chromium-enriched yeast for three months.As a control
group,sixteen hyperlipidemic patients were given 4g oenotheria binnis seed oil daily for three
months. The blood lipidsand serum Cr were measured before and after the supplementation
ofchromium-enriched yeast or oenotheria binnis seed oil.Blood lipids and serum Cr of normal
adults were estimated too.The results showed that the serum Cr in hyperlipidemic patients was
lower obviously than in healthy people(3.58 vs 5.27nmo1/L).After sup-plementation of
chromium-enriched yeast, for hyperlipidemic patients,serum Cr increased markedly(3.58 vs
6.10nmol/L),erum TC TG,LDL-C decreased significantly,HDL-Cand HDL_2-C increased
obviously;for hy-perlipidemic patients complicated with NIDDM,there were similar changes in
serum Cr,TC,TG,LDL-C,HDL-C and HDL_2-C and serum LPO der-eased significantly;for diabetics
with normal blood lipids,only FBG decr-eased and HDL-C increased significantly, TC, TG and
LDL-C didn′tchange markedly,But there were no apparent differences in TC,TG,LDL一C,HDL-C
and serum Cr in those hyperlipidemic patients who weregiven oenotheria binnis seed oil The
effective rates were 97.4%, 97.6%,100%and97.6%to high TC,TG,LDL-C and low HDL-C
respectively inhyperlipidemic patients. The study demonstrated that chromium-enriched yeast
can regulateserum lipids,decreased TC,TG,LDL-C and in creased HDL-C and HDL_2-Cin
hyperlipidemic patients and the lipids were maintained at the normalvalue while FBG decreased
significantly when it was given to the NIDDMwith normal blood lipids. |
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Keywords: | chromium-enriched yeast hyperlipidemia NIDDM Serum chromium blood selenium blood GSH-px |
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