The significance of H. pylori eradication in NSAIDs ulcer |
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| Authors: | Kato Mototsugu Ono Shouko Mabe Katsuhiro Shimizu Yuichi Asaka Masahiro |
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| Affiliation: | Division of Endoscopy, Hokkaido University Hospital. |
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| Abstract: | The significance of H. pylori eradication for NSAIDs induced gastroduodenal ulcer has not been clarified. NSAIDs and H. pylori infection are independent causal factors for gastroduodenal mucosal injuries. However, the interaction between these two factors is complicated. H. pylori eradication can reduce the risk of NSAIDs induced ulcer in NSAIDs naive patients. However, H. pylori eradication is not recommended in NSAIDs user because of no ulcer suppression and ulcer healing delay. In prevention of NSAIDs induced ulcer recurrence, H. pylori eradication plus PPI treatment is necessary. |
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