| 颅咽管瘤全切除术后血钠紊乱分析及治疗 |
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| 引用本文： | 周忠清,石祥恩,梁冶矢,张永力,刘波,钱海.颅咽管瘤全切除术后血钠紊乱分析及治疗[J].中国微侵袭神经外科杂志,2008,13(8). |
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| 作者姓名： | 周忠清 石祥恩 梁冶矢 张永力 刘波 钱海 |
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| 作者单位： | 周忠清 (北京三博脑科医院神经外科,北京,100093) ； 石祥恩 (北京三博脑科医院神经外科,北京,100093) ； 梁冶矢 (北京大学人民医院神经外科,北京,100034) ； 张永力 (北京三博脑科医院神经外科,北京,100093) ； 刘波 (北京大学人民医院神经外科,北京,100034) ； 钱海 (北京三博脑科医院神经外科,北京,100093) ； |
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| 摘 要： | 目的总结颅咽管瘤全切除术后血钠紊乱的发生规律和治疗方法。方法回顾性分析46例颅咽管瘤病人术后血钠紊乱的情况,分析血钠紊乱与病人年龄、肿瘤位置的关系。结果术后出现血钠紊乱者42例(91.3%),其中单纯低钠型9例(19.6%),单纯高钠型6例(13.0%),混合型血钠紊乱27例(58.7%)。42例术后血钠紊乱者中,术后3个月内恢复正常40例;1例持续高钠血症者在术后1.5年恢复正常;另1例持续高钠血症者术后2个月死于肺栓塞。15例儿童病人中7例在围手术期出现癫疒间发作,31例成年病人无一例出现癫疒间发作。结论颅咽管瘤全切除后血钠紊乱的发生率显著高于术前(P<0.001);术后血钠紊乱的类型与年龄、肿瘤复发、肿瘤囊实性和肿瘤位置无关(P>0.05)。纠正血钠紊乱是儿童颅咽管瘤病人在围手术期预防癫疒间发作的关键。
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| 关 键 词： | 颅咽管瘤 低钠血症 高钠血症 尿崩症 |
Analysis and treatment of sodium disturbance in patients after total removal of craniopharyngioma |
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| Institution: | ZHOU Zhongqing1; SHI Xiang en1; LIANG Yeshi2; et al. 1. Department of Neurosurgery; Beijing Sanbo Brain Hospital; Beijing 100093; China; 2. Department of Neurosurgery; Peking University People s Hospital; Beijing 100034; |
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| Abstract: | Objective To study sodium disturbance and its treatment in patients undergoing total removal of craniopharyngioma. Methods Forty-six cases of craniopharyngioma surgically treated were analyzed retrospectively. The relations of the sodium disturbance to age and location of tumor was analyzed. Results Forty-two patients (91.3%) had sodium disturbance after surgery. There were three types of sodium disturbance: simple hyponatremia in 9 (19.6%), simple hypernatremia in 6 (13.0%) and mixed type of sodium disturb... |
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| Keywords: | craniopharyngioma hyponatremia hypernatremia diabetes insipidus |
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