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凋亡与几种常见的肺疾病
引用本文:邹琳,刘长庭. 凋亡与几种常见的肺疾病[J]. 国际呼吸杂志, 2009, 29(16). DOI: 10.3760/cma.j.issn.1673-436X.2009.016.009
作者姓名:邹琳  刘长庭
作者单位:解放军总医院南楼呼吸科,北京,100853;解放军总医院南楼呼吸科,北京,100853
基金项目:全军医药卫生专项项目,武器装备预研基金,民用航天预先研究项目,北京市科技计划项目 
摘    要:凋亡是细胞的主动死亡过程,此过程涉及一系列基因的激活、表达和调控.在细胞的正常发育过程中,约有半数细胞通过凋亡途径被清除.20世纪80年代,凋亡开始成为研究热点,从凋亡角度探讨肺疾病的发生机制取得了一些进展,也为将来从凋亡角度治疗肺疾病奠定了基础.本文就细胞凋亡在几种常见肺疾病的发生机制研究中的最新进展作一综述.

关 键 词:凋亡  急性肺损伤  慢性阻塞性肺疾病  支气管哮喘

Apoptosis and some common lung diseases
ZOU Lin,LIU Chang-ting. Apoptosis and some common lung diseases[J]. International Journal of Respiration, 2009, 29(16). DOI: 10.3760/cma.j.issn.1673-436X.2009.016.009
Authors:ZOU Lin  LIU Chang-ting
Abstract:Apoptosis is a process of cellular active death, which is involved in a series of genes'activation,expression and control. In the normal development process of cells, half of cells are removed by apoptosis. Apoptosis has become study topic since 1980s, and some progress of lung diseases' pathogenesis from apoptosis" view were achieved,which provided some evidences for the treatment of lung diseases in the future. The review focuses on the recent advancement of apoptosis in some common lung diseases pathogenesis.
Keywords:Apoptosis  Acute lung injury  Chronic obstructive pulmonary disease  Bronchial asthma
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