Hb O Padova in a Spanish Family |
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Authors: | G Martín A Villegas F Calero S del Palacio J C López M López D Espinós |
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Affiliation: | Residencia Campo Ara?uelo, Navalmoral de la Mata (Cáceres), Espa?a. |
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Abstract: | Haematological and biochemical aspects of a new family with heterozygous Hb O Padova [alpha 30(B11) Glu----Lys] is described. This variant has been found on a screening programme of abnormal haemoglobin in cord blood. It was separated by cellulose acetate, isoelectric focusing, citrate agar, DEAE-cellulose chromatography and by cation exchange high-performance liquid chromatography. The heat stability and the functional properties were found to be normal. This is the third family with Hb O Padova reported, all from the Mediterranean region. |
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