肾移植患者输血产生群体反应性抗体分析

目的探讨肾移植患者输血与群体反应性抗体产生的关系。方法选择2004年3月至2007年4月肾移植前500例患者,其中输血患者180例。采用美国One lanmbda公司和美国GTI公司抗原板检测群体反应性抗体。结果180例肾移植前输血的患者中,男性66例,女性114例。男性和女性PRA阳性率分别为12.10%(8/66)和18.40%(21/114)。结论输血是导致群体反应性抗体生成的重要因素之一,女性患者抗体产生的概率高于男性。

Relationship between Kidney Transplantation Transfusion and Panel Reactive Antibody.

Objective To study the relationship between prekidney transplantation transfusion and panel react, yeantibody（PRA）, Methods From Mar. 2004 to Apr.2007,there were totall 500 patients Including180 pat, ents which hadbeen transfused before the kidney transplantation. The PICA ranges were analyzed by antigen detected trays（ One lanmbdaand GTI company）. Results The 180patients Including 66male and 114 female were detected. The positive rate ofmaleand female patients were 12.10%（8/66）and 18.40%（21/114） respectively. Conclusion Transfusion Is one of Important factors In PRA. The Incidence offemale patients with antlbodyls hlgherthan thatofmalepatlents.