| 以血小板减少为主的艾滋病病例临床分析 |
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| 引用本文： | 买买提艾力·吾布力,潘珂君,张韬,依巴古力·艾拜都拉,努力比亚·阿不都克尤木,张跃新. 以血小板减少为主的艾滋病病例临床分析[J]. 新疆医科大学学报, 2012, 35(3): 339-341 |
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| 作者姓名： | 买买提艾力·吾布力 潘珂君 张韬 依巴古力·艾拜都拉 努力比亚·阿不都克尤木 张跃新 |
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| 作者单位： | 新疆医科大学第一附属医院感染性疾病中心,乌鲁木齐,830011 |
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| 基金项目： | 国家科技重大专项资助项目 |
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| 摘 要： | 目的探讨以血小板减少为主要临床表现的艾滋病(AIDS)患者的临床特点、治疗方法、随访情况及转归。方法 10例AIDS患者使用高效抗逆转录病毒治疗(依非韦伦/奈韦拉平+司他夫定+拉米夫定),观察CD4细胞计数和血小板计数改变情况。结果 10患者治疗后6个月,血小板计数由平均(31.3±18.7)×109/L上升至(138.0±76.0)×109/L;CD4细胞计数由平均的(170.1±82.9)个/μL上升至(319.9±173.6)个/μL,均有明显改善;无机会性感染及HIV相关的死亡事件出现。结论及时开展高效抗逆转录病毒治疗,可有效改善以血小板减少为主要表现的艾滋病患者的预后及转归。
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| 关 键 词： | 艾滋病 血小板减少 高效抗逆转录病毒治疗 |
Clinical analysis of AIDS base on thrombocytopenia |
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| Maimaitiaili Wubuli , PAN Ke-jun , ZHANG Tao , Yibaguli Abaidula , Nulibiya Abudukeyoumu , ZHANG Yue-xin. Clinical analysis of AIDS base on thrombocytopenia[J]. Journal of Xinjiang Medical University, 2012, 35(3): 339-341 |
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| Authors: | Maimaitiaili Wubuli PAN Ke-jun ZHANG Tao Yibaguli Abaidula Nulibiya Abudukeyoumu ZHANG Yue-xin |
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| Affiliation: | (Center of Infectious Diseases,The First A f filiated Hospital,Xinjiang Medical University, Urumqi 830011,China) |
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| Abstract: | Objective To investigate the clinical features,treatment,follow-up and outcome of the 10 AIDS patients with clinical manifestations of thrombocytopenia as the main features admitted to departments.Methods With highly active anti-retroviral therapy,the change of CD4 cell count and platelet count were analyzed.Results After highly active anti-retroviral therapy,follow-up 6 months,platelet count from(31.3±18.768)×109/L to(138±76.092)×109/L;and CD4 count from(70.1±82.933) per/UL to(319.9±173.69) per/UL;They were significantly improved,no opportunistic infections and HIV-related deaths occurred.Conclusion A timely highly active anti-retroviral therapy can effectively improve the AIDS patients′ prognosis and outcome with thrombocytopenia as the main manifestation. |
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| Keywords: | AIDS thrombocytopenia highly active anti-retroviral therapy |
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