Insulin-like growth factor-binding protein PP12 in ovarian cyst fluid |
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| Authors: | M. Seppälä G. Than |
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| Affiliation: | (1) Department I of Obstetrics and Gynecology, Helsinki University Central Hospital, SF-00290 Helsinki, Finland;(2) Department of Obstetrics and Gynecology, University of Pécs, Pécs, Hungary |
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| Abstract: | Summary Elevated levels of insulin-like growth factor-binding protein (IGF-bp) were recently found in the serum of patients with ovarian tumors. We studied the concentration of IGF-bp in cyst fluids of 37 women operated on for benign or malignant ovarian cysts. The levels were elevated (>47  g/l) in 6 of 28 benign, but in none of the nine malignant ovarian cysts. The highest IGF-bp concentration (447 g/l) was observed in a benign serous cystadenoma. |
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| Keywords: | IGF-binding protein Placental protein 12 Ovarian tumors |
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