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Nuclear Magnetic Resonance Spectrum of Lysine-Vasopressin in Aqueous Solution and Its Structural Implications |
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| Authors: | P. H. Von Dreele A. I. Brewster J. Dadok H. A. Scheraga F. A. Bovey M. F. Ferger V. Du Vigneaud |
| Affiliation: | *Department of Chemistry, Cornell University, Ithaca, New York 14850;†Bell Telephone Laboratories, Murray Hill, New Jersey 07974;‡Department of Chemistry, Carnegie-Mellon University, Pittsburgh, Pennsylvania 15213 |
| Abstract: | The peaks in the proton NMR spectrum of lysine-vasopressin in aqueous solution at pH 3-5 were assigned to particular amino-acid residues by the use of the results of dilution studies and NH-CαH and CαH-CβH decoupling experiments. The conformation of lysine-vasopressin in water differs from its conformation in dimethylsulfoxide. |
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