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453例病毒性重型肝炎的临床特征及其防治意义
引用本文:黄仲德 沈耕荣. 453例病毒性重型肝炎的临床特征及其防治意义[J]. 天津医药, 1992, 20(2): 90-93
作者姓名:黄仲德 沈耕荣
作者单位:天津市传染病医院,上海第二医科大学附属瑞金医院,沈阳中国医科大学附属二、三院,重庆医科大学附属二院 300192,300192,300192,300192
摘    要:本文453例重肝中,急性重型40例(8.8%),亚急性重型413例(91.2%)。乙肝总感染率为78.4%,非甲非乙型为19.6%。肝中HDAg阳性检出率为4.8%(5/104例),其中上海、天津和沈阳地区分别为4.5%、11.5%及1.7%。 324例有肝性脑病。Ⅰ°—Ⅳ°肝性脑病者病死率分别为0%、15.2%、42.9%及83.8%。凝血酶原活动度>60%、30%~60%和<30%患者的病死率分别为0%、20.1%及57.8%。常见并发症为出血(53.2%)、继发性感染(33.8%)及肝肾综合征(15.0%)。对采用的六种新疗法疗效作了初步评价。

关 键 词:重症肝炎 临床特征 病毒性肝炎

Clinical Features of Severe Viral Hepatitis and Their Significance
Huang Zhongde,et al National Severe Hepatitis Coopereted Group Tianjin Infectious Diseases Hospital. Clinical Features of Severe Viral Hepatitis and Their Significance[J]. Tianjin Medical Journal, 1992, 20(2): 90-93
Authors:Huang Zhongde  et al National Severe Hepatitis Coopereted Group Tianjin Infectious Diseases Hospital
Abstract:In 453 patients with viral severe hepatitis (SVH), acute SVH and subacute SVHaccounted for 8.8% and 91.2% respectively. Total infectious rate for HBV was78.4% and the rate for Non-A, Non-B was 19.6%. The positive rate of hepatitis Dantigen in the liver was 4.8%. 307 of the 453 patients had hepatoencephalopathy.The mortality rates of the patients with hepatocoma from one to four grade were0%, 16.9%, 41.5%, and 90.1% respectively. Prothrombin activity correlated inverselywith the death rate of SVH patients. Essential complications included hemorr-hage, secondary infection and hepatorenal syndrome. Six new therapeutic methodswere used in these cases.
Keywords:severe viral hepatitis  clinical characteristics  
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