| 青霉素V钾片包衣处方研究及稳定性考察 |
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| 引用本文： | 李标,徐洁,蒲道俊.青霉素V钾片包衣处方研究及稳定性考察[J].中国医院用药评价与分析,2009(4):289-290. |
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| 作者姓名： | 李标 徐洁 蒲道俊 |
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| 作者单位： | 西南药业股份有限公司,重庆市400038 |
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| 摘 要： | 目的：通过研究不同包衣处方对青霉素V钾片进行包衣,并考察稳定性。方法：采用水溶性防潮包衣材料和醇溶性防潮包衣材料分别对青霉素V钾片进行包衣,并就其质量稳定性进行对比。结果：采用醇溶防潮包衣的青霉素V钾片,具有较佳的防潮性能和稳定性。结论：利用醇溶防潮包衣材料进行青霉素V钾片薄膜包衣,产品质量稳定,值得广泛应用。
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| 关 键 词： | 青霉素V钾片 稳定性 水溶性防潮包衣 醇溶性防潮包衣 |
Formulation of Coating Material and Stability of Potassium Phenoxymethylpenicillin Tablets |
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| LI Biao,XU Jie,PU Dao-jun.Formulation of Coating Material and Stability of Potassium Phenoxymethylpenicillin Tablets[J].Evaluation and Analysis of Drug-Use in Hospital of China,2009(4):289-290. |
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| Authors: | LI Biao XU Jie PU Dao-jun |
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| Institution: | (Southwest Pharmaceutical Co. Ltd. , Chongqing 400038, China) |
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| Abstract: | OBJECTIVE： To optimize the coating material for potassium Phenoxymethylpenicillin coated tablets and study its stability. METHODS： Potassium Phenoxymethylpenicillin coated tablets were prepared using water-soluble moisture - proof coating material and alcohol - moisture - proof coating material, respectively. Then the stability was compared between the two kinds of tablets. RESULTS： The tablets with alcohol - moisture - proof coating material showed better moisture - proof property and stability. CONCLUSION： The tablets with alcohol - moisture - proof coating material were proved to be stable in quality and which thus deserve to be used extensively. |
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| Keywords: | Potassium phenoxymethylpenicillin tablet Stability Water- soluble moisture - proof coating Alcohol - moisture - proof coating |
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