复方苦参注射液联合化疗治疗晚期小细胞肺癌的临床研究

目的：评价复方苦参注射液（岩舒注射液）对晚期小细胞肺癌化疗的增效减毒作用。方法：治疗组41例采用复方苦参注射液联合化疗,对照组44例行单纯化疗,化疗方案相同。2～6个周期后判定疗效。结果：（1）治疗组近期疗效优于对照组,差异有统计学意义（P＜0.05）;（2）各主要系统的毒副反应治疗组较对照组减轻（P＜0.05）;（3）化疗后生存质量改善方面,治疗组优于对照组（P＜0.05）。结论：复方苦参注射液联合化疗能提高临床疗效,减轻化疗不良反应,提高患者生存质量。

Clinical Efficacy of Compound Kusheng Injection Combined Chemotherapy for Advanced Small-cell Lung Cancer

OBJECTIVE： To evaluate the synergistic and attenuating effect of Compound Kusheng injection（Yanshu injection）on chemotherapy adopted for patients with advanced small-cell lung cancer（SCLC）.METHODS： 41 cases in treatment group were assigned to receive Compound Kusheng injection in combination of chemotherapy,44（control group）to receive chemotherapy alone.After treatment for 2 to 6 cycles,the curative effects in the two groups were evaluated.RESULTS：（1）There were significant differences between the treatment group and the control group in short - term curativeeffect（better in treatment group than in control group, P 〈 0.05）. （2）The toxicity in the treatment group was milder than in the control group（ P 〈 0.05 ）. （3）The treatment group had better improvement than in control group in the quality of life after undergoing chemotherapy （ P 〈 0.05 ）. CONCLUSION ： Compound Kusheng injection can improve the clinical curative efficacy but reduce the toxicity of chemotherapy while improving the quality of life in patients with advanced small - cell lung cancer.