| 血管生成素2的研究进展 |
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| 引用本文： | 陈海红,吴求亮.血管生成素2的研究进展[J].医学分子生物学杂志,2005,2(2):129-131. |
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| 作者姓名： | 陈海红 吴求亮 |
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| 作者单位： | 浙江大学医学院附属第一医院耳鼻咽喉科,杭州市,310003;浙江大学医学院附属第一医院口腔颌面外科,杭州市,310003 |
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| 摘 要： | 血管生成素(angiopoietin,Ang)是近年来发现的与血管新生密切相关的一个新家族,包括Ang-1、Ang-2、Ang-3、Ang-4,参与胚胎血管的发生及成年机体生理、病理性血管形成,尤其Ang-2,在肿瘤组织中的表达明显高于周围正常组织。
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| 关 键 词： | 血管生成素2 血管新生 肿瘤 |
| 修稿时间： | 2004年6月3日 |
Advances in the Research of Angiopoietin-2 |
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| CHEN Haihong,WU Qiuliang.Advances in the Research of Angiopoietin-2[J].Journal of Medical Molecular Biology,2005,2(2):129-131. |
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| Authors: | CHEN Haihong WU Qiuliang |
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| Institution: | CHEN Haihong~1,WU Qiuliang~2 1 Department of Otorhinolaryngology,the First Affiliated Hospital,Medical College of Zhejiang University,Hangzhou,310003,China 2 Department of Maxillary and Oral Surgery,the First Affiliated Hospital,Medical College of Zhejiang University,Hangzhou,310003,China |
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| Abstract: | The family of angiopoietins (Ang) is a newly discovered family which is intimately related to the vascular development. Now, four more members of the family have been identified: Ang-1, Ang-2, Ang-3 and Ang-4, They are critical for the vasculogenesis and angiogenic remodelling physiologically and pathologically both in embryonic stage and adults. Especially higher expression of Ang-2 has been detected in neoplasms than in normal tissues. |
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| Keywords: | angiopoietin-2 angiogenesis tumor |
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