10例药物性高催乳素血症分析

目的高催乳素血症是一种下丘脑-垂体-性腺轴功能紊乱所致的疾病,患者多未就诊或首诊于其他专科,易漏诊和误诊。方法排除其他原因所致的高PRL血症,在停用可疑药物的同时,给予溴隐停治疗。结果 2例患者曾怀疑为特发性高PRL血症,予以溴隐停治疗,服药后自觉症状改善,停用避孕药后血PRL完全恢复正常。其余8例患者均停用可疑药物(2例为替换)后,自觉症状逐渐改善(最快者仅1周),高PRL血症在1～3月后逐渐降至正常范围。结论在临床工作中应重视和加强对高PRL血症的警觉和筛查,准确及时诊治,才能避免漏诊和误诊。

10 Cases of Drug-induced Hyperprolactinemia Analysis

Objective Hyperprolactinemia is a hypothalamic-pituitary-gonadal axis dysfunction caused by disease,patients with multiple treatment or first diagnosis of other specialties,easily missed diagnosis and misdiagnosis.Methods Rule out other causes of high PRL hyperlipidemia,and disable the suspicious drugs at the same time,given the BRC treatment.Results Two cases of patients with suspected idiopathic PRL viremia to be BRC treatment,symptoms improved after taking the blood PRL disable contraceptives completely back to normal.The remaining 8 patients were disabled after the suspected drug（two cases replace）,the symptoms gradually improved（the fastest one week）,high PRL hyperlipidemia gradually decreased to normal range after March.Conclusion In clinical work should pay attention to and strengthen the awareness and screening of high PRL hyperlipidemia,accurate and timely diagnosis and treatment in order to avoid misdiagnosis and missed diagnosis.