| 脐血与成人血成分、T淋巴细胞亚群及正常人骨髓集落形成的比较研究 |
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| 引用本文： | 孙爱励,胡晓东,吴待英,王兆军. 脐血与成人血成分、T淋巴细胞亚群及正常人骨髓集落形成的比较研究[J]. 白血病．淋巴瘤, 2001, 10(2): 84-86 |
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| 作者姓名： | 孙爱励 胡晓东 吴待英 王兆军 |
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| 作者单位： | 河北省医学科学院,河北,石家庄,050021 |
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| 基金项目： | 河北省科技厅科研项目;95216121; |
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| 摘 要： | 目的：研究脐血，成人外周血及骨髓的特性，方法：采用全自动血细胞分析仪及流式细胞仪分别测定济血，成人外周血的血成分及T巴细胞亚群，采用集落形成试验观察脐血，外周因及骨髓的CTU－GM和BFU－E的产率变化，结果：脐血的各种血成分均显著高于外周血，CD，CD3明显低于外周血，而CD4，CD8的表达与外周血相似，经细胞因子诱导后，脐血中的CUF0－GM及BFU－E显著升高，结论：脐血富含造血干细胞，是重建造血与免疫系统的血细胞新来源。
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| 关 键 词： | 脐血 外周血 骨髓 T淋巴细胞亚群 集落形成单位 |
| 文章编号： | 1009-9921(2001)02-0084-03 |
| 修稿时间： | 1999-07-12 |
THE COMPARATIVE STUDIES ON BLOOD COMPANENTS, LYMPHOCYTE SUBSETS AND COLONY FORNING UNIT IN CORD BLOOD ,PERIPHERAL BLOOD AND BONE MARROW |
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| SUN Ai-li,HU Xiao-dong,WU Dai-ying,et al Hebei Acadmy of Medical Sciences. THE COMPARATIVE STUDIES ON BLOOD COMPANENTS, LYMPHOCYTE SUBSETS AND COLONY FORNING UNIT IN CORD BLOOD ,PERIPHERAL BLOOD AND BONE MARROW[J]. Journal of Leukemia & Lymphoma, 2001, 10(2): 84-86 |
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| Authors: | SUN Ai-li HU Xiao-dong WU Dai-ying et al Hebei Acadmy of Medical Sciences |
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| Abstract: | Objective:To study characteristied of cord blood, peripheral blood and bone marrow.Methods:Using autoanalytics,flow cytometric immunoassy and colony forming unit.Results:The components and CD_2,CD_3 increased markedly in cord blood than peripheral blood,but the expression of CD_4,CD_8 on cord blood was similar to peripheral blood.The mononuclear cells were cultrured in vitro CFU-GM and BFU-E of cord blood were increased significantly than another two.Conclusion:The cord blood have rich hematopoietic stem cells.They are a new source of hematopoietic cell which can rebuild hemopoiesis and immune system. |
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| Keywords: | Cord blood Peripheral blood Bone marrow Lymphocyte substes Colony forming unit |
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