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| 染色体变异与男性不育 | |
| 引用本文： | 宋兰林,郑少斌,汪吉仪,邢福祺.染色体变异与男性不育[J].南方医科大学学报,2000,20(6):548. |
| 作者姓名： | 宋兰林 郑少斌 汪吉仪 邢福祺 |
| 作者单位： | 1. 第一军医大学南方医院，内分泌科，广东 广州 510515 2. 第一军医大学南方医院，泌尿外科，广东 广州 510515 3. 第一军医大学南方医院 妇产科，广东 广州 510515 |
| 摘 要： | 目的 探讨染色体异常与男性不育的关系。方法 对565例男性不育患者进行染色体分析。结果 发现染色体异常69例，异常率为12.21%。其中性染色体异常48例，占异常核型 69.75%；性反转综合征1例，占异常核型1.45%；常染色体异常20例，占异常核型28.98%。结论 染色体异常是造成男性不育的重要遗传因素。提示对精液检查异常者或男性性征发育不良者进行染色体检查，将有助于不育病因的诊断。 |
| 关 键 词： | 男性不育 染色体 异常核型 |
| 文章编号： | 1000-2588（2000）06-0548-01 |
| 修稿时间： | 2000年8月26日 |
The chromosome anomalies relative with male infertility |
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| SONG Lan-lin,ZHENG Shao-bin,WANG Jie-yi,XING Fu-qi.The chromosome anomalies relative with male infertility[J].Journal of Southern Medical University,2000,20(6):548. | |
| Authors: | SONG Lan-lin ZHENG Shao-bin WANG Jie-yi XING Fu-qi |
| Institution: | SONG Lan-lin1,ZHENG Shao-bin2,WANG Jie-yi3,XING Fu-qi1 |
| Abstract: | Objective To explore the relationship between chromosomal anomalies and infertility in male. Methods Chromosomal analyses of 565 cases of male infertility were performed. Results Abnormal karyotype were detected in 69 cases (12.21%), among which 48 (69.75%) were categorized as sex-chromosome abnormalities, 20 (28.98%) were autosome aberrance, and 1 (1.45%) was sex reversal. Conclusion The chromosomal anomalies are important inheritance factor for male sterility. Chromosomal analysis of the patients with abnormal semen or underdeveloped secondary sexual characteristics may be of significance in the diagnoses of infertility. |
| Keywords: | male infertility chromosome abnormal karyot |
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