潜伏期妊娠梅毒168例临床及母婴传播干预分析

目的:探讨潜伏期妊娠梅毒的临床预后及不同驱梅治疗时机胎传梅毒的发生.方法:总结168例潜伏期妊娠的梅毒妊娠不良结局,根据驱梅治疗时机分为早、中孕治疗组和晚孕、未治疗组,比较两组先天梅毒的发生.结果:168例患者中,宫外孕20例(11.9%),自然流产10例(5.95%),死胎死产5例(2.98%),人工流产或引产13例...

The Analysis of Clinical and Intervention of Maternal-fetal Transmission in 168 Latent Syphilis During Pregnancy

Objective： To investigate the adverse pregnant outcomes and congenital syphilis in various time of treatment of pregnant women with latent syphilis.Method： The adverse pregnant outcome in 168 pregnant women with latent syphilis was studied.The patiens were divided into two groups based on the time of treatment： early-midterm pregnancy group and late pregnancy or non-treatment group.The incidence rate of congenital syphilis were compared between the two groups.Result： 168 pregnant women with latent syphilis,included 20 patients with extrauterine（11.9%）,10 patients with natural abortion（5.95%）,5 paitents with fetal death or stillbirth（2.98%）,13 patients with artificial abortion.The incidence rate of in 111 alive infants,the incidence rate of congenital syphilis was 19.6%（11/56） in early-midterm pregnancy group,83.6%（46/55） in late pregnancy or non-treatment group.The difference was significant between them（X2=45.5,P0.01）.Conclusion： The incidence rate of adverse pregnant outcomes is very high in pregnant women with latent syphilis.Early detect and early therapy are key measures for blocking maternal-fetal transmission of latent syphilis during pregnancy.